QPIx colony picker, bacterial colonies, yeast colonies, phage display system

Unmatched for productivity and performance

Developed from world-class QPix robotics, the new QPix 400 series of microbial colony pickers offers the unique option to simultaneously detect colonies and quantify fluorescent markers in a pre-screening step before picking.

More than just colony pickers, these systems enable scientists to:

Automate workflows from sampling and spreading to picking
Pick the right colonies every time
Efficiently manage large, diverse populations for: protein expression, biofuel research, enzyme evolution, phage display, DNA sequencing, library generation and management

QPix systems are used worldwide in over 600 installations in research institutes, sequencing facilities, biotech and pharmaceutical companies. QPix robotics developed a reputation for reliability and accuracy, when used in sequencing centers during the Human Genome project.

Shorten timelines, eliminate unnecessary work and expense downstream

Use unique information to identify the best colonies
Pre-screen colonies using white light and fluorescent imaging
Accurately pick up to 30,000 selected colonies per day from trays or dishes

Support more applications

Objective, quantitative pre-screening
Track fluorescent proteins
- Compatible with broad range of fluorescent cloning vectors
- Fuse fluorescent proteins with others to study protein folding or secretion, enzyme evolution or protein localization
- Use as transformation markers or for mutation screens

Example: fast track development of constructs or target proteins

Automate and track entire workflow from spreading* transformed cells to colony picking
Pre-screen to identify colonies with optimal expression levels
Accurately pick colonies of interest
Maintain subsequent clonal integrity

All colonies detected in white light

Colonies expressing required level of target protein identified in fluorescent channel

Selected colonies ready for picking

Unmatched performance

Pick the right colony every time
- Use unique information to identify the best colonies
- Pre-screen colonies using white light and fluorescent imaging
Picking efficiency >98%
- Organism-specific pins maximize material transfer
- Automatic calculation of agar height increases accuracy
Track entire sample history
- Enhance visibility of history and location – tag important samples
- Record and track sample histories from sample spreading* to picking, replication and re-arraying

Review an entire plate in a single view

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High speed operation - accurate colony picking

Systems tailored to workload and application requirements

QPix 460

With a fully automated workflow, provides the greatest flexibility in application and experimental design

Automatically sample and spread from 1 x 96 well source plate into bioassay every 30 min.
Up to 140 destination plates in 2 stacker lanes
Sets up screening assays on filters or agar
Cherry-picks selected clones after off-line analysis